Table 3

Conservation of promiscuous epitopes

Epitope core

Protein

DRB1 alleles predicted to bind

Conservation


VRAMSSLGS

PPE18

0101, 0401, 0404, 0405, 0802, 0901, 1101, 1301, 1501

Unconserved

MILIATNLL

PPE18

0101, 0401, 0404, 1301, 1302, 1501

Unconserved

MVSMANNHM

PPE18

0101, 0401, 0404, 0405, 1301, 1302

Unconserved

YVAWMSVTA

PPE18

0101, 0401, 0404, 0405, 1101

Conserved

LLGQNTPAI

PPE18

0101, 0401, 0404, 1301

Conserved

ILIATNLLG

PPE18

0101, 0401, 0404, 1301, 1501

Unconserved

ISNMVSMAN

PPE18

0101, 0401, 0404, 0405, 1101

Unconserved

LFSAASAFQ

PPE18

0101, 0401, 0405, 0901

Conserved

YVMPHSPAA

PPE18

0101, 0401, 0405, 0802

Unconserved

VSMTNTLSS

PPE18

0101, 0401, 0404, 0405

Unconserved

VVGMNTAAS

PepA

0101, 0301, 0401, 0404, 0405, 0802, 1101, 1301, 1501

Conserved

VVLTNNHVI

PepA

0101, 0405, 0701, 0802, 1101, 1301, 1302, 1501

Conserved

VVGSAPAAS

PepA

0101, 0404, 0802, 0901, 1101, 1301

Conserved

FLGLGVVDN

PepA

0101, 0401, 0405, 1101

Conserved

LRGAGGLPS

PepA

0101, 0802, 1101, 1301

Conserved


McNamara et al. BMC Immunology 2010 11:18   doi:10.1186/1471-2172-11-18

Open Data