Table 4

The multinomial distribution of a promoter with its RNAP and two regulatory TFs.

(TF1, TF2) RNAP

(0, 0)

(1, 0)

(0, 1)

(1, 1)


0

1

qTF1

qTF2

wTF1TF2 qTF1 qTF2

1

qp

wTF1 p qTF1 qp

wTF2 p qTF2 qp

(wTF1 p+ wTF2 p) wTF1TF2 qTF1 qTF2 qp


The state of the promoter is represented by the row name and the column name. For example, the first row and the second column has RNAP=0 and (TF1, TF2)=(1,0), which means the promoter is bound by TF1 only. The quantity in a cell represents the ratio between the probability of a particular state and the probability of the base state (no RNAP binding and no TF binding).

Chen et al. BMC Genomics 2008 9(Suppl 1):S18   doi:10.1186/1471-2164-9-S1-S18

Open Data