Genomic region that contains one protein binding site. A. Relative likelihood of RNase digestion at each genomic locus. B. Similarity between the distribution of experimentally-detected amplicons and simulated amplicons assuming protein binding occurs at the each locus. A higher correlation coefficient implies higher probability of protein binding. C. Distribution of detected RNA fragments. D. Distribution of simulated fragments based on the best prediction locus (marked as blue ellipse).
Wang et al. BMC Genomics 2008 9(Suppl 1):S17 doi:10.1186/1471-2164-9-S1-S17