Figure 6.

p53 interactome along with the putative miR regulators that are shown to be repressed following the activation of p53 [11]. miRNAs are represented by yellow ellipses, target genes are represented by green boxes. p53 is represented in the center as blue circle. Induction of the miRNAs by p53 is represented by directed red lines. Negative regulation of the target genes by miRNAs are represented by dark grey lines. The protein interactions are represented by undirected light blue lines. Networks (using force-directed layouts) were generated using aiSee [76] network visualization software.