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Open Access Research article

Predicted transcription factor binding sites as predictors of operons in Escherichia coli and Streptomyces coelicolor

Emma Laing12, Khushwant Sidhu1 and Simon J Hubbard1*

Author Affiliations

1 Faculty of Life Sciences, The University of Manchester, Michael Smith Building, Oxford Road, Manchester, M13 9PT, UK

2 School of Biomedical and Molecular Sciences, University of Surrey, Guildford, GU2 7XH, UK

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BMC Genomics 2008, 9:79  doi:10.1186/1471-2164-9-79

Published: 12 February 2008

Additional files

Additional file 1:

Operon definitions used in this study. This file contains list of operonic and non-operonic genes used in the datasets tested in this study, for Streptomyces coelicolor and E. coli. Data sets are divided into known operons, non-operon gene pairs at known transcriptional boundaries, and non-operon genes from triplet data where genes are transcribed in opposite directions.

Format: DOC Size: 242KB Download file

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Open Data

Additional file 2:

Repressor and Activator site footprint data. This file contains full details of all the 211 repressor sites, 77 activator sites and 341 dual regulator sites taken footprint data in RegulonDB for E. coli and used in this study for analysing trends in palindromicity.

Format: DOC Size: 564KB Download file

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Open Data