Research article
In silico discovery of transcription regulatory elements in Plasmodium falciparum
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* Corresponding author: Elizabeth A Winzeler winzeler@scripps.edu
1 Department of Cell Biology, ICND 202, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
2 Department of Cellular and Molecular Medicine, University of California - San Diego, La Jolla, CA, USA
3 Department of Bioengineering, University of California - San Diego, La Jolla, CA, USA
4 Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA
5 Department of Cell Biology and Neuroscience, University of California - Riverside, Riverside, CA, USA
BMC Genomics 2008, 9:70 doi:10.1186/1471-2164-9-70
Published: 7 February 2008Additional files
Additional File 1:
Sporozoite-specific OPI cluster seed genes. The 18 P. falciparum sporozoite-related genes used to seed OPI generation of the sporozoite-specific gene cluster GO:GNF0006.
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Additional File 2:
OPI clusters used for GEMS analysis. The 21 OPI clusters used as the basis for GEMS analysis listed by GO identifier number and cluster size.
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Additional File 3:
Putative promoter cis-regulatory elements discovered by GEMS. Motif derived from GEMS analysis of 1000 base pair promoter regions upstream of gene start codons.
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Additional File 4:
Putative intron cis-regulatory elements discovered by GEMS. Motif candidates derived from GEMS analysis of gene intron regions.
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Additional File 5:
Differentially expressed genes in response to heat shock. Top 75 differentially expressed genes in response to heat shock treatment identified by microarray hybridization and non-parametric Mack-Skillings test.
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Additional File 6:
P. falciparum mitochondrial TCA cycle gene expression. Life cycle mRNA expression values for P. falciparum mitochondrial TCA cycle genes as determined by microarray hybridization.
Format: XLS Size: 30KB Download file
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