Resolution:
## Figure 3.
Differential expression of miRNA in PKD and control (Ctrl) animals. Heatmap was produced using simultaneous clustering of rows and columns of the data
matrix using complete linkage algorithm and a euclidean distance metric. Prior to
clustering, values were transformed to zero (row-wise) mean and unit (row-wise) variance.
The miRNA clustering tree is shown on the left and the sample clustering tree is shown
on the top. The samples are clustering broadly into two groups, control (Ctrl) and
PKD. The color scale shown at the right illustrates the relative expression level
of the indicated miRNA across all samples: red denotes expression > 0 and blue denotes
an expression < 0. miRNAs shown here are from miRNA microarrays.
Pandey |