BMC Genomics

official impact factor 4.21

Open Access Methodology article

Evaluating genome-wide DNA methylation changes in mice by Methylation Specific Digital Karyotyping

Kathy Boon1*, John K Tomfohr1, Nathaniel W Bailey1, Stavros Garantziotis1, Zhuowei Li2, David M Brass1,2, Shuichiro Maruoka1, John W Hollingsworth2 and David A Schwartz1,3,4

Author Affiliations

1 National Heart Lung and Blood Institute/National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA

2 Duke University Medical Center, Durham, NC 27710, USA

3 National Jewish Health, Denver, CO 80206, USA

4 University of Colorado Health Sciences Center, Denver, CO 80206, USA

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BMC Genomics 2008, 9:598 doi:10.1186/1471-2164-9-598

Published: 11 December 2008

Additional files

Additional file 1:

Differentially methylated genomic tags and nearest genes. Files 1 and 2 catalogs respectively the 82 genomic sequence tags with higher counts in the LMD library. Also indicated are the nearest genes.

Format: DOC Size: 293KB Download file

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Open Data

Additional file 2:

Differentially methylated genomic tags and nearest genes. Catalogs the 71 genomic sequence tags with higher counts in the HMD MSDK library representing differentially methylated loci within the mouse genome. Also indicated are the nearest genes.

Format: DOC Size: 238KB Download file

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Open Data

Additional file 3:

Differentially expressed SAGE transcripts. Represents the transcript tags significantly over expressed in the HMD SAGE library.

Format: DOC Size: 355KB Download file

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Open Data

Additional file 4:

Differentially expressed SAGE transcripts. Represents the transcript tags significantly over expressed in the LMD SAGE library.

Format: DOC Size: 2.9MB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data