Open Access Research article

Overcoming function annotation errors in the Gram-positive pathogen Streptococcus suis by a proteomics-driven approach

Manuel J Rodríguez-Ortega1*, Inmaculada Luque2, Carmen Tarradas2 and José A Bárcena1

Author Affiliations

1 Departamento de Bioquímica y Biología Molecular, Universidad de Córdoba, 14071 Córdoba, Spain

2 Departamento de Sanidad Animal, Universidad de Córdoba, Spain

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BMC Genomics 2008, 9:588  doi:10.1186/1471-2164-9-588

Published: 5 December 2008

Additional files

Additional file 1:

Peptides identified by LC/MS/MS. The Excel document contains the peptides identified for all the proteins reported in this study after trypsin and proteinase K treatment of Streptococcus suis strain 235/02.

Format: XLS Size: 24KB Download file

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Additional file 2:

Proteins annotated as ribonucleases G and E in bacteria. The Word file contains a list of all the proteins predicted as ribonucleases G and E in bacteria, according to the non-redundant UniProt Knowledgebase. Entries are sorted by alphabetical order of UniProt codes.

Format: DOC Size: 54KB Download file

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Additional file 3:

Proteins with similarity to Ssu05_1371. The Word file contains a list of proteins from Gram-positive organisms showing significant similarity to Ssu05_1371 through BLAST search. All the proteins found have the cell wall-anchoring LPXTG motif.

Format: DOC Size: 43KB Download file

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Additional file 4:

GO annotations of identified proteins. The Excel file contains the gi identifiers, Uniprot codes, GO annotations and GO evidence codes for the proteins coded in the reported loci and identified in this study.

Format: XLS Size: 42KB Download file

This file can be viewed with: Microsoft Excel Viewer

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