Table 3

Probe sets identified as dose-responsive for permethrin.


Linear Regression (SAM)
 Isotonic Regression (PIR)
 ANOVA
Affymetrix Probe Set I.D.
 Gene Symbol
 di
 p-value
 q-value
 Mi
 p-value
 q-value
 p-value
1369303_at
 Crh
 4.26
 0.0001
 0.00
 1.92
 0.0003
 1.00
 0.0113
1368677_at
 Bdnf**
 3.85
 0.0003
 0.00
 1.52
 0.0025
 1.00
 0.0170
1370412_at
 Slc40a1
 -3.50
 0.0006
 0.18
 -1.70
 0.0016
 1.00
 0.0050
1370415_at
 Rassf5**
 3.37
 0.0008
 0.12
 1.85
 0.0004
 1.00
 0.0170
1375043_at
 c-fos**
 3.23
 0.0012
 0.18
 1.41
 0.0045
 1.00
 0.0170
1395991_at
 Rimbp2
 3.11
 0.0016
 0.28
 1.39
 0.0050
 1.00
 0.0400
1388583_at
 Cxcl12
 2.92
 0.0027
 0.42
 1.36
 0.0057
 1.00
 0.0477
1368321_at
 Egr1**
 2.87
 0.0030
 0.50
 1.21
 0.0132
 1.00
 0.0230
1369067_at
 Nr4a3
 2.77
 0.0040
 0.55
 1.15
 0.0187
 1.00
 0.0270
1387025_at
 Dync1i1
 2.76
 0.0041
 0.55
 1.29
 0.0085
 1.00
 0.0208
1381557_at
 Gna14
 2.67
 0.0052
 0.61
 1.87
 0.0004
 1.00
 0.0176
1387024_at
 Dusp6
 2.59
 0.0064
 0.75
 1.01
 0.0398
 1.00
 0.0230
1388911_at
 Prim2
 2.50
 0.0082
 0.79
 1.45
 0.0036
 1.00
 0.0408
1385778_at
 Siat7E
 2.36
 0.0116
 0.79
 1.43
 0.0041
 1.00
 0.0305
1395272_at
 LOC682937
 -1.88
 0.0394
 0.69
 -1.33
 0.0084
 1.00
 0.0305
1367652_at
 Igfbp3
 1.38
 0.1190
 0.79
 1.35
 0.0063
 1.00
 0.0358
1389090_at
 Wrnip1
 1.32
 0.1319
 0.79
 1.30
 0.0079
 1.00
 0.0170
1376602_a_at
 Fbxo22
 0.89
 0.2974
 1.32
 1.27
 0.0096
 1.00
 0.0186
1391301_at
 LOC682355
 0.51
 0.5404
 1.32
 1.35
 0.0062
 1.00
 0.0305

** = genes examined by qRT-PCR. Positive SAM di or PIR Mi scores denote upregulated probe sets. Negative SAM di or PIR Mi scores denote downregulated probe sets. A full list of probe sets altered by deltamethrin exposure, including predicted protein coding sequences and expressed sequence tags is given in Additional file 4.

Harrill et al. BMC Genomics 2008 9:546   doi:10.1186/1471-2164-9-546