Table 2

Probe sets identified as dose-responsive for deltamethrin.



Linear Regression (SAM)
Isotonic Regression (PIR)
ANOVA
Affymetrix Probe Set I.D.
Gene Symbol
di
p-value
q-value
Mi
p-value
q-value
p-value

1371363_at
Gpd1**
5.63
0.0000
0.00
2.34
0.0000
0.24
0.0032
1388901_at
Fkbp51**
5.46
0.0000
0.00
2.21
0.0000
0.42
0.0051
1367577_at
Hsp27**
4.60
0.0001
0.00
1.90
0.0002
0.97
0.0195
1369560_at
Gpd1**
4.53
0.0001
0.00
1.91
0.0002
1.00
0.0134
1368064_a_at
Ddc**
-4.35
0.0001
0.14
-1.95
0.0002
1.00
0.0195
1391229_at
Camk1g**
4.22
0.0002
0.00
2.11
0.0000
0.51
0.0063
1380611_at
Fkbp51**
3.90
0.0004
0.11
1.62
0.0012
1.00
0.0276
1369303_at
Crh
3.62
0.0009
0.11
1.73
0.0006
1.00
0.0276
1388271_at
LOC689415
3.48
0.0013
0.19
1.44
0.0037
1.00
0.0300
1370989_at
Ret
3.38
0.0017
0.19
1.49
0.0028
1.00
0.0300
1370026_at
Cryab
3.28
0.0022
0.29
1.46
0.0032
1.00
0.0364
1374626_at
Lrg1
3.23
0.0025
0.33
1.45
0.0036
1.00
0.0323
1376709_at
Slc39a8
-3.07
0.0038
0.14
-1.49
0.0026
1.00
0.0364
1368650_at
Klf10
-3.07
0.0038
0.14
-1.30
0.0077
1.00
0.0356
1380329_at
Tmem10
-3.03
0.0041
0.14
-1.28
0.0086
1.00
0.0496
1372564_at
Ets2
3.03
0.0042
0.51
1.41
0.0045
1.00
0.0396
1389507_at
Nedd4l
2.97
0.0048
0.51
1.42
0.0043
1.00
0.0306
1375138_at
Timp3
2.92
0.0054
0.56
1.22
0.0134
1.00
0.0319
1370530_a_at
Pld1
-2.81
0.0071
0.14
-1.34
0.0062
1.00
0.0493
1385778_at
Siat7E
2.79
0.0075
1.15
1.38
0.0055
1.00
0.0276
1395986_at
Slit2
-2.78
0.0077
0.14
-1.27
0.0094
1.00
0.0419
1369973_at
Xdh
2.76
0.0080
1.15
1.18
0.0167
1.00
0.0472
1368438_at
Pde10a
2.70
0.0094
1.16
1.11
0.0255
1.00
0.0496
1387260_at
Klf4
-2.69
0.0096
0.14
-1.49
0.0026
1.00
0.0429
1372356_at
Usp54
2.69
0.0097
1.16
1.12
0.0240
1.00
0.0442
1371442_at
Hyou1
2.68
0.0099
1.16
1.03
0.0384
1.00
0.0467
1375296_at
LOC684097
2.66
0.0105
1.16
1.40
0.0047
1.00
0.0427
1398899_at
Polr2c
2.64
0.0110
1.16
1.67
0.0009
1.00
0.0195
1377518_at
Camk1g**
2.59
0.0123
1.16
1.29
0.0090
1.00
0.0315
1372090_at
Max
2.53
0.0143
1.16
1.31
0.0080
1.00
0.0306
1381557_at
Gna14
2.35
0.0216
1.16
1.29
0.0087
1.00
0.0442
1398373_at
B3galt3
2.29
0.0248
1.16
1.29
0.0091
1.00
0.0396
1372037_at
Pdlm7
2.18
0.0319
1.16
1.28
0.0098
1.00
0.0351
1382112_at
LOC682926
-2.16
0.0333
1.15
-1.26
0.0096
1.00
0.0344
1375752_at
Bves
-1.96
0.0519
1.15
-1.41
0.0042
1.00
0.0376
1370869_at
Bcat1
1.92
0.0561
1.16
1.28
0.0096
1.00
0.0345
1367706_at
Vdac1
1.74
0.0820
1.16
1.29
0.0090
1.00
0.0295

** = genes examined by qRT-PCR. Positive SAM di or PIR Mi scores denote upregulated probe sets. Negative SAM di or PIR Mi scores denote downregulated probe sets. A full list of probe sets altered by deltamethrin exposure, including predicted protein coding sequences and expressed sequence tags is given in Additional file 3.

Harrill et al. BMC Genomics 2008 9:546   doi:10.1186/1471-2164-9-546