Changes in plasma metabolite concentrations during fasting. A) Glucose and lactate (mM, primary Y-axis), and ammonia concentrations (μM, secondary Y-axis) after 0, 12, 24, 48 and 72 hours of fasting. B) Adaptive changes in concentrations of a selection of amino acids during fasting (those without significant change between any two time points were left out). For all the metabolites measured: 8 < n < 12; bars represent SEM and the asterisks identify significant changes (P < 0.05) in comparison to the fed condition.
Sokolović et al. BMC Genomics 2008 9:528 doi:10.1186/1471-2164-9-528