The ORF variability patterns differ between wine and clinical strains. The consensus karyoscope maps obtained for wine (Panel-A) and clinical (Panel-B) strains showed that ORF variation in wine strains was distributed along chromosomes while in clinical strains such distribution was more frequent in sub-telomeric regions. The consensus maps show the relative percentage of strains (percent of samples) within wine (Panel-A) and clinical (Panel-B) environments with copy number alteration in a given ORF, relatively to the reference strain S288C. The data was plotted according to ORF chromosome location. Red bars represent percentage of strains with amplifications and green bars represent the percentage of strains with deletions, according to the grey-line scale shown above and below the chromosome central line. Open circles indicate the position of centromeres and blue arrows identify Ty elements.
Carreto et al. BMC Genomics 2008 9:524 doi:10.1186/1471-2164-9-524