Figure 2.

Novel protein-sequence space generated by parts of retrocopies combined with other transposons or unusual events. For each part of the figure, the spliced parent mRNA is shown first (before retroposition) and the resulting gene(s) are shown below. New sequence space was triggered by a combination of retrogene insertions, recruitment of non-genic regions including retroposons, whereby the contribution of the retrocopy's original in-frame ORF is very small (see text and legend to Fig. 1 including color key for further details). Yellow boxes with grey vertical stripes and yellow medium size bars correspond to retroposed element contributions to ORFs and UTRs, respectively. For detailed descriptions see text.