Table 6

Fold changes of the mRNA levels of the cell growth-related genes in male and female hepatocyte RXRα-deficient mouse livers.

6 month male mice (KO vs. WT)

6 month female mice (KO vs. WT)


Name

Fold Change

function

Name

Fold Change

function


LCN2

6.37

oncogene

LCN2

4.57

oncogene

PIM1

4.10

oncogene

GFRA1

2.15

oncogene

MAFB

4.07

oncogene

PTTG1

-4

oncogene

ERBB3

2.05

oncogene

PROM1

-5.61

oncogene

REL

-2.34

oncogene

PLAGL1

-2.09

suppressor

MDM2)

-2.47

oncogene

KLF6

-2.19

suppressor

JUN

-2.87

oncogene

WWOX

-2.2

suppressor

RHOB

-2.93

oncogene

CAPG

-2.23

suppressor

PTTG1

-2.95

oncogene

KLF4

-2.32

suppressor

RHOC

-3.06

oncogene

GJA1

-2.91

suppressor

ROS1

-3.14

oncogene

GSN

-3.18

suppressor

SERTAD1

-3.7

oncogene

PEG3

-5.96

suppressor

PML

-3.9

oncogene

TPM1

-11.95

suppressor

ETS2

-4.97

oncogene

FOS

-5.74

oncogene

MYC

-7.7

oncogene

SOCS3

3.85

suppressor

MAD1L1

3.73

suppressor

TCF21

2.82

suppressor

CEBPD

2.77

suppressor

SSBP2

2.27

suppressor

NDRG1

2.19

suppressor

HMGN1

2.1

suppressor

SLC22A18

2.08

suppressor

AIM1

2.05

suppressor

KSR1

2.04

suppressor

CDKN1A

-2.32

suppressor

MBL2

-2.34

suppressor

GSN

-2.42

suppressor

TPM1

-2.46

suppressor

PSRC1

-2.78

suppressor

GPX3

-2.8

suppressor

PERP

-3.42

suppressor

MSX1

-3.5

suppressor

MBD1

-4.15

suppressor

BTG2

-5.26

suppressor

KLF6

-5.67

suppressor

EGR2

-6.03

suppressor

EGR1

-15.88

suppressor

24 month male mice (KO vs. WT)

24 month female mice (KO vs. WT)


Name

Fold Change

function

Name

Fold Change

function


JUN

2.29

oncogene

LIMK1

4.9

oncogene

PTTG1

2.25

oncogene

ROS1

4.51

oncogene

PLK3

3.91

suppressor

CCND1

4.44

oncogene

BLNK

2.13

suppressor

APC

2.87

oncogene

GPX3

2.11

suppressor

MAFB

2.57

oncogene

BEXL1

2.08

suppressor

MYBL2

2.54

oncogene

WWOX

-2.00

suppressor

SH2B2

2.25

oncogene

PEG3

-2.2

suppressor

PDGFB

2.23

oncogene

WISP1

-3.48

suppressor

E2F3

2.08

oncogene

PERP

-4.03

suppressor

FLT4

2.02

oncogene

MYCL1

-2.08

oncogene

GPC1

-2.09

oncogene

CDK5

-2.11

oncogene

DCT

-2.3

oncogene

SH3RF1

-2.35

oncogene

NKX2-5

-2.42

oncogene

BANP

3.97

suppressor

PEG3

2.91

suppressor

IFI16

2.63

suppressor

BLNK

-2.55

suppressor

DKK3

-4.13

suppressor

GPR65

-6.82

suppressor


Guo et al. BMC Genomics 2008 9:403   doi:10.1186/1471-2164-9-403

Open Data