Table 4

Fold changes of the mRNA levels of the metastasis-related genes in male and female hepatocyte RXRα-deficient mouse livers.

6 month male mice (KO vs. WT)

6 month female mice (KO vs. WT)


Name

Fold Change

Function

Name

Fold Change

function


ARHGDIB

-2.05

anti-metastasis

BRMS1

-2.16

anti-metastasis

KRT18

-2.15

anti-metastasis

CD36

-2.88

anti-metastasis

CD36

-2.16

anti-metastasis

MYO10

2.63

pro-metastasis

KRT19

-2.43

anti-metastasis

ROCK1

-2.24

pro-metastasis

THBS1

-7.11

anti-metastasis

CTTN

-2.88

pro-metastasis

SERPINE1

-23.48

anti-metastasis

ITGA6

-3.64

pro-metastasis

CAV1

2.86

pro-metastasis

FN1

2.67

pro-metastasis

ID2

2.65

pro-metastasis

DDEF1

2.52

pro-metastasis

CLCA1

2.33

pro-metastasis

S100A10

-2.09

pro-metastasis

ADAM12

-2.12

pro-metastasis

CNN2

-2.16

pro-metastasis

PLAUR

-2.25

pro-metastasis

PLAT

-2.30

pro-metastasis

NEDD9

-2.39

pro-metastasis

SPP1

-2.75

pro-metastasis

CTGF

-2.90

pro-metastasis

VIM

-3.25

pro-metastasis

LGALS7

-3.79

pro-metastasis

EPHA2

-4.71

pro-metastasis

24 month male mice (KO vs. WT)

24 month female mice (KO vs. WT)


Name

Fold Change

Function

Name

Fold Change

function


TIMP4

4.07

anti-metastasis

DDR1

-2.20

anti-metastasis

ANK3

2.07

anti-metastasis

TFF3

11.22

pro-metastasis

LGALS3

2.00

anti-metastasis

ADAM15

3.38

pro-metastasis

TFF3

4.05

pro-metastasis

MMP9

2.49

pro-metastasis

CTGF

2.22

pro-metastasis

ITGB1

2.48

pro-metastasis

MT1E

2.19

pro-metastasis

CSF2RB

2.32

pro-metastasis

CAV1

2.15

pro-metastasis

FOXM1

2.13

pro-metastasis

PLAUR

2.03

pro-metastasis

MYO6

-4.70

pro-metastasis

PTP4A3

-2.55

pro-metastasis


Guo et al. BMC Genomics 2008 9:403   doi:10.1186/1471-2164-9-403

Open Data