Table 3

Fold changes of the mRNA levels of the apoptosis-related genes in male and female hepatocyte RXRα-deficient mouse livers.

6 month male mice (KO vs. WT)

6 month female mice (KO vs. WT)


Name

Fold Change

function

Name

Fold Change

function


FKBP5

4.26

anti-apoptosis

FKBP5

2.63

anti-apoptosis

USP2

3.46

anti-apoptosis

USP2

2.17

anti-apoptosis

CFLAR

2.56

anti-apoptosis

BCL6

2.14

anti-apoptosis

BGN

2.4

anti-apoptosis

SERPINA3K

2.06

anti-apoptosis

BIK

4.41

pro-apoptosis

BGN

-2.12

anti-apoptosis

ACVR2B

3.55

pro-apoptosis

ANP32A

-2.01

pro-apoptosis

BNIP2

2.09

pro-apoptosis

CASP8

-2.04

pro-apoptosis

EMP2

-2.7

pro-apoptosis

DUSP6

-4.26

pro-apoptosis

BCL2L11

-5.61

pro-apoptosis

24 month male mice (KO vs. WT)

24 month female mice (KO vs. WT)


Name

Fold Change

function

Name

Fold Change

Function


USP2

3.97

anti-apoptosis

IER3

2.23

anti-apoptosis

FKBP5

2.81

anti-apoptosis

BCL6

2.08

anti-apoptosis

IER3

2.8

anti-apoptosis

BIK

2.22

pro-apoptosis

DUSP1

2.3

anti-apoptosis

WNK1

-2.35

pro-apoptosis

BIRC4

-3.19

anti-apoptosis

DIABLO

-2.87

pro-apoptosis

CASP1

2.83

pro-apoptosis

UBE1L

2.36

pro-apoptosis

ZBTB16

2.19

pro-apoptosis

SOX9

-2.09

pro-apoptosis

CASP8

-2.27

pro-apoptosis


Guo et al. BMC Genomics 2008 9:403   doi:10.1186/1471-2164-9-403

Open Data