Table 6

Differentially expressed genes related to purine/pyrimidine metabolism in artesunate-treated cells

Gene ID

Description

ART 90 min

ART 3 h

HS

CQ


PF14_0697

dihydroorotase, putative

0,96

0,93

PF13_0259

cytidine and deoxycytidylate deaminase family, putative

-1,22

PF10_0121

hypoxanthine phosphoribosyltransferase

-1,24

PF11_0282

deoxyuridine 5'-triphosphate nucleotidohydrolase, putative

-0,88

-0,95

PFE0660c

purine nucleotide phosphorylase, putative

-1,07

-1,53


Gene ID: identifier as found in PlasmoDB.

Art columns: log ratios of gene expression under artesunate exposure at 90 minutes and 3 hours.

Results were compared with transcriptome modifications induced by heat-shock (HS) [12] and chloroquine (CQ) [8].

Genes were selected based on [16].

Natalang et al. BMC Genomics 2008 9:388   doi:10.1186/1471-2164-9-388

Open Data