Table 5

Differentially expressed genes related to the mitochondrion in artesunate treated cells

Gene ID

Description

ART 90 min

ART 3 h

HS

CQ


PF08_0054

heat shock 70 kDa protein

0,88

+

coxI

putative cytochrome oxidase I

-1,07

coI

putative cytochrome oxidase I

-1,15

PF14_0248

ubiquinol-cytochrome c reductase hinge protein, putative

-0,99

-

PFC0975c

PFCYP19, cyclophilin, peptidyl-prolyl cis-trans isomerase

-0,97


Gene ID: identifier as found in PlasmoDB.

Art columns: log ratios of gene expression under artesunate exposure at 90 minutes and 3 hours.

HS column: over (+) or under (-) expression.

Results were compared with transcriptome modifications induced by heat-shock (HS) [12] and chloroquine (CQ) [8].

Genes were selected based on [16].

Natalang et al. BMC Genomics 2008 9:388   doi:10.1186/1471-2164-9-388

Open Data