Table 4

Differentially expressed genes involved in lipid metabolism in artesunate-treated cells

Gene ID

Description

ART 90 min

ART 3 h

HS

CQ


MAL13P1.485

acyl-coa ligase antigen

0,94

PFB0685c

acyl-CoA synthetase, PfACS9

0,83

PFB0695c

acyl-CoA synthetase

0,88

1,02

+

PF14_0761

fatty acyl CoA synthetase 1 PfACS1

0,99

PF14_0664

biotin carboxylase subunit of acetyl CoA carboxylase, putative

0,97

1,31

+

PF08_0099

acyl CoA binding protein, putative

-0,89

PF10_0016

acyl CoA binding protein, putative

-1,04

-

PFE0410w

triose or hexose phosphate/phosphate translocator, putative

-0,88

-


Gene ID: identifier as found in PlasmoDB.

Art columns: log ratios of gene expression under artesunate exposure at 90 minutes and 3 hours.

HS column: over (+) or under (-) expression.

Results were compared with transcriptome modifications induced by heat-shock (HS) [12] and chloroquine (CQ) [8].

Genes were selected based on [16].

Natalang et al. BMC Genomics 2008 9:388   doi:10.1186/1471-2164-9-388

Open Data