Table 1

Differentially expressed genes involved in antioxidant defence in artesunate-treated cells

Gene ID

Description

ART 90 min

ART 3 h

HS

CQ


PFI0925w

gamma-glutamylcysteine synthetase

1,41

+

PFE0605c

glutathione synthetase

0,94

PFL0595c

glutathione peroxidase

-0,95

PF11_0352

protein disulfide isomerase related protein

-0,89

-


Genes coding for proteins involved in antioxidant defence defined in [23].

Gene ID: identifier as found in PlasmoDB.

Art columns: log ratios of gene expression under artesunate exposure at 90 minutes and 3 hours.

HS column: over (+) or under (-) expression.

Results were compared with transcriptome modifications induced by heat-shock (HS) [12] and chloroquine (CQ) [8].

Natalang et al. BMC Genomics 2008 9:388   doi:10.1186/1471-2164-9-388

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