Table 2

Direct hypothesis category of yeast genes shown by microarray analysis to be affected by berenil treatment

ORF

Gene

Ratio

Function

Process


YBR233W-A

DAD3

-3.45

mitosis

protein binding activity

Q0130

OLI1

-2.75

ATP synthase activity

ATP synthesis coupled proton transport

YDR070C

FMP16

-2.43

unknown

unknown

YEL039C

CYC7

-2.41

electron transport

electron carrier activity

YLR327C

TMA10

-2.35

unknown

unknown

YJL156W-A

YJL156W-A

-2.25

unknown

unknown

YMR105C

PGM2

-2.23

glucose 1-phosphate utilization

phosphoglucomutase activity

YGR248W

SOL4

-2.00

unknown

unknown

YHR087W

YHR087W

-1.95

unknown

unknown

YPR160W

GPH1

-1.76

glycogen catabolism

glycogen phosphorylase activity

YLR178C

TFS1

-1.76

regulation of proteolysis

lipid binding activity

YOR173W

DCS2

-1.72

unknown

unknown

YEL011W

GLC3

-1.66

glycogen metabolism

1,4-alpha-glucan branching enzyme activity

YMR081C

ISF1

-1.64

aerobic respiration

unknown

YER150W

SPI1

-1.51

unknown

unknown

YER067W

YER067W

-1.50

unknown

unknown

YOR031W

CRS5

-1.45

response to metal ion

copper ion binding activity

YIL136W

OM45

-1.43

unknown

unknown

YPL230W

YPL230W

-1.41

unknown

unknown

YOR178C

GAC1

-1.38

meiosis

protein phosphatase type 1 activity

YFR053C

HXK1

-1.35

fructose metabolism

hexokinase activity

YOR120W

GCY1

-1.33

salinity response

aldo-keto reductase activity

YFR017C

YFR017C

-1.32

unknown

unknown

YOR374W

ALD4

-1.31

ethanol metabolism

aldehyde dehydrogenase (NAD+) activity

YJR096W

YJR096W

-1.29

arabinose metabolism

oxidoreductase activity

YFR015C

GSY1

-1.27

glycogen metabolism

glycogen (starch) synthase activity

YDR453C

TSA2

-1.22

regulation of redox homeostasis

thioredoxin peroxidase activity

YHL021C

FMP12

-1.21

unknown

unknown

YKL151C

YKL151C

-1.15

unknown

unknown

YGR008C

STF2

-1.14

ATP synthesis

unknown

YDL130W-A

STF1

-1.09

ATP synthesis

unknown

YCL042W

YCL042W

-1.08

unknown

unknown

YOR385W

YOR385W

-1.07

unknown

unknown

YIL045W

PIG2

-1.07

unknown

protein phosphatase regulator activity

YLR258W

GSY2

-1.06

glycogen metabolism

glycogen (starch) synthase activity

YMR173W

DDR48

-1.04

DNA repair

unknown

YNL015W

PBI2

-1.03

vacuole fusion (non-autophagic)

endopeptidase inhibitor activity

YCL040W

GLK1

-1.02

carbohydrate metabolism

glucokinase activity

YAR071W

PHO11

1.02

phosphate metabolism

acid phosphatase activity

YKL099C

UTP11

1.18

processing of 20S pre-rRNA

snoRNA binding activity


Genes hypothesized to be directly affected by berenil treatment are listed with their expression ratios (log2 transformed treated to untreated) and functions, if known.

Eckdahl et al. BMC Genomics 2008 9:32   doi:10.1186/1471-2164-9-32

Open Data