Table 8

Enriched GO terms for genes regulated by switch-like transcription factors. Terms are organized by cellular component (CC), biological process (BP), and molecular function (MF). Enrichment scores are the number of observed genes over the number of expected genes. P-values were computed using the hypergeometric distribution.

GO term

Genes observed

Genes expected

Ration of enrichment

P-values ≤ 0.001

CC

collagen type I

2

0.04

48.58

4.18E-04

external side of plasma membrane

6

0.93

6.48

2.70E-04

extracellular matrix (sensu Metazoa)

8

1.63

4.92

1.80E-04

extracellular region

14

4.43

3.16

9.44E-05

extracellular space

30

13.44

2.23

5.68E-06

MHC class I protein complex

3

0.14

20.82

2.77E-04

BP

antigen processing and presentation of endogenous peptide antigen via MHC class I

2

0.04

48.58

4.18E-04

antigen processing and presentation of peptide antigen via MHC class I

3

0.14

20.82

2.77E-04

defense response

6

1.01

5.95

4.34E-04

glucose transport

4

0.23

17.67

4.92E-05

immune response

11

3.23

3.40

3.07E-04

rhythmic process

3

0.19

16.19

6.45E-04

MF

extracellular matrix structural constituent

5

0.56

9.00

1.84E-04

structural constituent of bone

2

0.04

48.58

4.18E-04

Ertel and Tozeren BMC Genomics 2008 9:3   doi:10.1186/1471-2164-9-3