Figure 2.

Histogram showing the number of AIS subfamilies with each system-level function category. Each bar shows the number of AIS subfamilies that have each system-level function category. Asterisks indicate statistically significant enrichment of categories (P < 0.05, calculated using hypergeometric distribution with Bonferroni correction). BM, bone marrow; MT, muscle tissue; RepO, reproductive organ; ResO, respiration organ; Epi, epithelium; IO, internal organ and metabolism system; AIS, adaptive immune system; II, innate immunity; NS, nervous system.