Resolution:
## Figure 7.
Volume of expression by position with respect to segment boundaries – estimated from
expression data. With respect to (a) A+/T+ boundaries; (b) T+/A+ boundaries. For both graphs, the
unsymmetric black line shows the volume of transcription along one strand from left
to right – transcription with the flow of the segment bias is on the right for (a),
and on the left for (b). The peak is about 15 kb to 20 kb downstream/upstream of the
segment boundary. Corresponding data for both sides of the boundary have been averaged.
The upper red line plots the sum of the amounts on the two strands and the blue line
plots their absolute difference. All three lines show moving averages over 100 bases
and the thickness of the lines show 95% confidence limits. For both (a) and (b), a
two-tailed z-test shows that the black line at position +5000 bases is statistically
different from that at position -5000: a) p < 10^{-50}, n1 ~ 2058, n2 ~ 856, z = 16.5: b) p < 10^{-50}, n1 ~ 2253, n2 ~ 1260, z = 16.6.
Evans |