A comparison of segment bias and transcription bias. The black line shows the AT-bias about the A+/T+ boundary. The red line shows the AT-bias for genes aligned by their TSS: for this line the x-axis gives the position relative to the TSS. Both lines show moving averages over 100 bases. The thickness of both lines show 95% confidence limits. There is a statistically significant difference between the two lines: at position 5000 bases downstream of the boundary a two-tailed z-test gives p-value < 10-50 n1 = 11750, n2 = 23941, z = -63.
Evans BMC Genomics 2008 9:16 doi:10.1186/1471-2164-9-16