Figure 3.

Chromosomal location of coregulated genes. Several differentially expressed genes show significant clustering in around Ppt1 on mouse chromosome 4, and might therefore be coregulated. The probesets for Ppt1 were excluded from the dataset and thus Ppt1 is shown in gray. The genes participating in the regulated loci or being independently regulated are shown, together with their location in base pairs in mouse chromosome 4. Genes that exhibit expression differences in both mouse models are indicated with *. Expression changes only in the Cln1-/- mouse are indicated with **.