Can subtle changes in gene expression be consistently detected with different microarray platforms?
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* Corresponding author: Peter AC 't Hoen p.a.c.hoen@Lumc.nl
1 Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands
2 Leiden Genome Technology Center, Leiden University Medical Center, Leiden, The Netherlands
3 Division of Medical Pharmacology, Leiden/Amsterdam Center for Drug Research, Leiden, The Netherlands
4 Department of Technology, Study Programme Bioinformatics, Hogeschool Leiden, Leiden, The Netherlands
5 Pediatric Oncology, Erasmus Medical Center, Rotterdam, The Netherlands
BMC Genomics 2008, 9:124 doi:10.1186/1471-2164-9-124
Published: 10 March 2008Additional files
Additional file 1:
suppl.material.pedotti. contains a more detailed comparison of the performance of AGL and AFF microarrays.
Format: DOC Size: 533KB Download file
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Additional file 2:
table.S1.pedotti. contains a list of the genes selected for the validation with qRT-PCR and its results.
Format: DOC Size: 93KB Download file
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Additional file 3:
table.S2.pedotti. contains the hybridization design for the two color arrays (AGL and LGTC).
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Additional file 4:
all.data.UG. contains the expression data of all the 5 platforms for the subset of genes with overlapping UG identifiers.
Format: TXT Size: 8.7MB Download file
