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Open Access Highly Accessed Research article

The adaptive evolution of the mammalian mitochondrial genome

Rute R da Fonseca124, Warren E Johnson3, Stephen J O'Brien3, Maria João Ramos1 and Agostinho Antunes134*

Author Affiliations

1 REQUIMTE, Departamento de Química, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre, 687, 4169-007 Porto, Portugal

2 Evolutionary Biology, Institute of Biology, University of Copenhagen, Universitetsparken 15, 2100 Copenhagen Ø, Denmark

3 Laboratory of Genomic Diversity, National Cancer Institute, Frederick, MD 21702-1201, USA

4 CIMAR/CIIMAR, Centro Interdisciplinar de Investigação Marinha e Ambiental, Universidade do Porto, Rua dos Bragas, 177, 4050-123 Porto, Portugal

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BMC Genomics 2008, 9:119  doi:10.1186/1471-2164-9-119

Published: 4 March 2008

Additional files

Additional file 1:

Supporting information. Saturation plots (S1), maximum likelihood tree (S2), number of strong positively selected amino acid properties plotted against the branch length (S3), number of strong positively selected amino acid properties across all sites in each mammalian mtDNA-encoded subunit of the respiratory chain (S4) and the sites indicated in Figure 10 in four elephant relatives and 6 alpaca relatives (S5).

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