Table 5

Comparison of features associated with protein aggregation between high abundant proteins and the remaining detected proteins. The high abundant group is defined as described in Material and Methods.

Property

Low abundant proteins Mean (Median)

High abundant proteins Mean (Median)

P-value KS-, MW-test

Protein length (in amino acids)

386 (327)

309 (252)

10^-6, 10^-7

Number of alternating hydrophobic-/hydrophilic stretches (> = 5aa)

11.7 (9.0)

9.5 (8.0)

0.03, 10^-4

pI distance from neutrality

1.52 (1.50)

1.69 (1,84)

0.003, 0.01

Hydrophobicity (Kyte-Doolite scale)

-0.20 (-0.21)

-0.25 (-0.24)

0.17, 0.08

Ishihama et al. BMC Genomics 2008 9:102   doi:10.1186/1471-2164-9-102