Table 10

TGF-β regulated genes (36) in A549 involved in regulation of actin cytoskeleton

Acc No

DAVID Gene Name

1 hr

4 hr

12 hr


H83405

FYVE, RHOGEF AND PH DOMAIN CONTAINING 1 (FACIOGENITAL DYSPLASIA)

0.57 ± 0.41

0.35 ±

0.26 ± 0.01

N45505

VAV 1 ONCOGENE

0.64 ± 0.37

0.41 ± 0.11

0.31 ± 0.01

N45518

NCK-ASSOCIATED PROTEIN 1

1.03 ± 0.12

1.76 ± 0.2

1.39 ± 0.18

AA046597

INTEGRIN, BETA 4

1.26 ± 0.21

1.1 ± 0.19

1.8 ± 0.18

R52046

ACTININ, ALPHA 4

1.26 ± 0.68

1.21 ±

1.81 ± 0.21

N42722

GUANINE NUCLEOTIDE BINDING PROTEIN (G PROTEIN), GAMMA 12

1.44 ± 0.04

1.5 ± 0.09

1.28 ± 0.17

AL598940

MYOSIN, LIGHT POLYPEPTIDE 1, ALKALI; SKELETAL, FAST

1.15 ± 0.01

1.33 ± 0.17

1.56 ± 0.02

BE738680

RAS HOMOLOG GENE FAMILY, MEMBER A

1.24 ± 0.11

1.4 ± 0.06

1.51 ± 0.03

H73472

CELL DIVISION CYCLE 42 (GTP BINDING PROTEIN, 25KDA)

1.24 ± 0.27

1.33 ± 0.07

1.56 ± 0.01

W17002

INTEGRIN, ALPHA V (VITRONECTIN RECEPTOR, ALPHA POLYPEPTIDE, ANTIGEN CD51)

1.21 ± 0.06

2.32 ± 0.29

2.73 ± 0.28

AA088648

FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME)

1.45 ± 0.24

1.97 ± 0.08

1.77 ± 0.09

N57424

T-CELL LYMPHOMA INVASION AND METASTASIS 1

1.35 ± 0.02

1.23 ± 0.04

1.34 ± 0.02

H10616

PROFILIN 2

1.44 ± 0.08

1.49 ± 0.11

1.1 ± 0

BM912016

P21(CDKN1A)-ACTIVATED KINASE 4

1.29 ± 0.03

1.1 ± 0.23

1.54 ± 0.03

H23109

FIBROBLAST GROWTH FACTOR 1 (ACIDIC)

0.94 ±

1.36 ± 0.01

1.13 ± 0.05

BM924824

RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1 (RHO FAMILY, SMALL GTP BINDING PROTEIN RAC1)

1.39 ± 0

1.41 ± 0.06

1.28 ± 0.18

H15287

P21(CDKN1A)-ACTIVATED KINASE 6

1.47 ± 0.08

1.21 ± 0.05

1.57 ± 0.04

T39460

PROTEIN PHOSPHATASE 1, CATALYTIC SUBUNIT, ALPHA ISOFORM

1.35 ± 0.17

1.38 ± 0.04

1.49 ± 0.15

BM888157

THYMOSIN, BETA 4, X-LINKED

1.02 ±

1.58 ±

1.93 ± 0.14

T83174

ACTIN RELATED PROTEIN 2/3 COMPLEX, SUBUNIT 1B, 41KDA

1.24 ± 0.08

1.06 ± 0.1

1.54 ± 0.04

AA127854

INTEGRIN, ALPHA 5 (FIBRONECTIN RECEPTOR, ALPHA POLYPEPTIDE)

1.4 ± 0.08

1.12 ± 0.03

1.22 ± 0.06

H27657

G PROTEIN-COUPLED RECEPTOR KINASE INTERACTOR 1

1.39 ± 0.09

1.11 ± 0.04

1.34 ± 0.25

N29131

MOESIN

1.37 ± 0.09

1.03 ± 0.06

1.42 ± 0.05

AA044582

INTEGRIN, BETA 8

0.33 ± 0.03

0.26 ± 0.04

0.25 ± 0

T77476

GUANINE NUCLEOTIDE BINDING PROTEIN (G PROTEIN), ALPHA 13

1.39 ± 0.41

1.59 ± 0.08

1.24 ± 0.14

R35167

BAI1-ASSOCIATED PROTEIN 2

1.46 ± 0.15

0.97 ± 0.02

1.32 ± 0.12

H06909

PROTEIN PHOSPHATASE 1, REGULATORY (INHIBITOR) SUBUNIT 12B

1.34 ± 0.03

1.16 ± 0.01

1.08 ± 0.03

H14999

RAC/CDC42 GUANINE NUCLEOTIDE EXCHANGE FACTOR (GEF) 6

0.22 ± 0.13

0.27 ± 0.14

0.28 ± 0

N77112

IQ MOTIF CONTAINING GTPASE ACTIVATING PROTEIN 1

1.6 ± 0.35

1.54 ± 0.13

1.48 ± 0.04

BI752921

PLATELET-DERIVED GROWTH FACTOR RECEPTOR, BETA POLYPEPTIDE

1.43 ± 0.09

1.03 ± 0.02

1.09 ± 0.07

N99223

INTEGRIN, ALPHA 9

1.46 ± 0.12

1.08 ±

1.29 ± 0.01

BI258438

COFILIN 1 (NON-MUSCLE)

1.24 ± 0.09

1.08 ± 0.09

1.42 ± 0.04

BQ017489

ACTININ, ALPHA 1

1.57 ± 0.22

1.24 ± 0.1

1.5 ± 0.1

H51445

LIM DOMAIN KINASE 1

1.3 ± 0

1.02 ± 0.11

1.12 ± 0.01

AA010526

GLUCOCORTICOID RECEPTOR DNA BINDING FACTOR 1

1.44 ± 0.14

1.03 ± 0.04

1.31 ± 0

AA043909

PTK2 PROTEIN TYROSINE KINASE 2

0.52 ± 0.11

0.52 ± 0.12

0.34 ± 0


For description see legend of table 5

Ranganathan et al. BMC Genomics 2007 8:98   doi:10.1186/1471-2164-8-98

Open Data