Effect of blocking the Integrin-linked signalling on the regulation of gene expression by TGF-β in A549 cells. The cells were grown to 90% confluence, washed with serum free medium, treated with 500 μg/ml GRGDNP peptide 3 hours prior to treatment with TGF-β. The cells were harvested after 12 hours following TGF-β treatment and processed for qRT-PCR as described in Figure 3.
Ranganathan et al. BMC Genomics 2007 8:98 doi:10.1186/1471-2164-8-98