Table 1

Differentially expressed genes of MSC after high grade expansion.

Passage 2 vs passage 5 Acc.No

Gene name

log2 ratio

Fold-change


XM_016240

hypothetical protein xp_016240; loc87477//Homo sapiens similar to keratinocyte growth factor-like protein, group II – human (LOC158116)

0.92

1.89

NM_006211_1

proenkephalin; penk

1.58

2.99

NM_001854_1

collagen, type xi, alpha 1; col11a1

1.27

2.41

BC010956_1

similar to fibroblast growth factor 7 (keratinocyte growth factor)

1.03

2.04

NM_000612_1

Insulin-like growth factor 2 (somatomedin A); igf2

1.59

3.01

NM_031476_1

hypothetical protein dkfzp434b044; dkfzp434b044

1.34

2.53

U52914_1

b219ob receptor isoform hub219.3 precursor

1.13

2.19

NM_006379_1

sema domain, immunoglobulin domain (ig), short basic domain, secreted, (semaphorin) 3c; sema3c

-0.69

0.62

NM_002546_1

osteoprotegerin; tnfrsf11b

-1.03

0.49

Passage 5 vs passage 10 Acc.No

NM_019105_1

tenascin xb

0.85

1.80


List of differentially expressed genes after statistical analysis by modified version of the regularized t-test [64] (p < 0.05) for ten donors (passage 2 vs. passage 5) and five donors (passage 5 vs. passage 10).

Kulterer et al. BMC Genomics 2007 8:70   doi:10.1186/1471-2164-8-70

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