Figure 3.

FISH of metaphase preparations depicting copy number alterations. A) CaSki – 5 chromosomes 5 (centromere 5-blue; TRIO-green; SKP2-red); one isochromosome 5p (yellow arrow), 2 translocations of RP11-1150G22, encompassing TRIO (green arrow) and 2 translocations of RP11-624K2, encompassing SKP2 (red arrow). B) CaSki – 3 chromosomes 8 (centromere 8-red, TUSC3-green) with loss of one copy the BACs encompassing TUSC3, RP11-44L18/184C1 (green arrow). C) HeLa – 4 chromosomes 20 (centromere 20-blue, ZNF-217-red, CYP24A1-green); one isochromosome 20q (yellow arrow).

Kloth et al. BMC Genomics 2007 8:53   doi:10.1186/1471-2164-8-53
Download authors' original image