BMC Genomics

official impact factor 4.21

Open Access Research article

Positional bias of general and tissue-specific regulatory motifs in mouse gene promoters

Nicolás Bellora1,2, Domènec Farré2 and M Mar Albà1,3,4*

Author Affiliations

1 Research Unit on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain

2 Centre for Genomic Regulation, Barcelona, Spain

3 Fundació Institut Municipal d'Investigació Mèdica, Barcelona, Spain

4 Catalan Institution for Research and Advanced Studies, Barcelona, Spain

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BMC Genomics 2007, 8:459 doi:10.1186/1471-2164-8-459

Published: 13 December 2007

Additional files

Additional file 1:

Additional file 1 contains average nucleotide composition along the promoter for real and synthetic datasets.

Format: PDF Size: 94KB Download file

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Additional file 2:

Additional file 2 contains motif clustering for motifs in Figure 2.

Format: PDF Size: 46KB Download file

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Additional file 3:

Additional file 3 contains results of motif positional bias searches using TRANFAC matrices, at p-value <= 10-5.

Format: XLS Size: 139KB Download file

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Additional file 4:

Additional file 4 contains results of motif positional bias searches using JASPAR CORE matrices, at p-value <= 10-5.

Format: XLS Size: 29KB Download file

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Additional file 5:

Additional file 5 contains results of motif positional bias searches using JASPAR phyloFACTS matrices, at p-value <= 10-5.

Format: XLS Size: 52KB Download file

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Additional file 6:

Additional file 6 contains results of motif positional bias searches using 6mers, at p-value <= 10-5.

Format: XLS Size: 106KB Download file

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Additional file 7:

Additional file 7 contains tissue clusters in which every pair of tissues shares at least 30% of the genes of restricted (RT) expression class.

Format: EPS Size: 1.1MB Download file

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Additional file 8:

Additional file 8 contains predictions of general motifs in mouse promoters, in significant regions described in Additional file 3.

Format: TXT Size: 11.5MB Download file

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Additional file 9:

Additional file 9 contains predictions of non-general motifs in mouse promoters, in significant regions described in Additional file 3.

Format: TXT Size: 77KB Download file

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Additional file 10:

Additional file 10 contains the data in Additional files 8 and 9 in BED format, for visualization using UCSC Genome Browser.

Format: ZIP Size: 3.2MB Download file

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