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Morphological characteristics of primary branches of the saphenous artery |
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| Parameter |
WKY |
ACTH |
SHR |
|
|
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| Systolic BP (mmHg) |
123 ± 5 (5) |
146 ± 3* (10) |
187 ± 4* (9) |
| Circumference (μm) |
745 ± 36 (4) |
628 ± 51 (7) |
610 ± 22 (6) |
| Mean SMC layers |
7.2 ± 0.1 (4) |
6.7 ± 0.4 (7) |
8.7 ± 0.4* (5) |
| Area of EC (μm2) |
392 ± 9 (5) |
438 ± 13* (6) |
279 ± 4* (3) |
| MEGJs/EC |
0.1 ± 0.08 (4) |
0.06 ± 0.04 (4) |
0.03 ± 0.03 (3) |
|
Mean ± SEM; number of animals in parentheses. *p < 0.05 compared to WKY. Myoendothelial gap junctions (MEGJs) are expressed per endothelial cell (EC). Measurement of EC area from 150 cells (WKY), 76 cells (ACTH) and 45 cells (SHR). SMC = smooth muscle cell. Data for WKY from reference [49]. | |||
Grayson et al. BMC Genomics 2007 8:404 doi:10.1186/1471-2164-8-404 |
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