Table 2

Genes selected for biological analysis

Gene name [Representative public ID]

Fold Change

q value


Genes overexpressed in TEL/AML1 positive ALL


Scavenger receptor class B, member 1 (SCARB1) [NM_005505]

2.12

< 0.01

Tumor necrosis factor receptor superfamily, member 7 (TNFRSF7) [NM_001242]

1.99

< 0.01

Tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) (TFPI) [NM_006287]

2.71

< 0.01

Activin A receptor, type IC (ACVR1C) [NM_145259]

1.95

< 0.01

Tumor protein p53 inducible nuclear protein 1 (TP53INP1) [NM_033285]

2.53

< 0.01

Core-binding factor, runt domain, alpha subunit 2; translocated to, 3 (CBFA2T3) [NM_005187]

3.45

< 0.01

Runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) (RUNX1) [NM_001754]

1.75

< 0.01

cDNA FLJ14565 fis, clone NT2RM4000233, highly similar to Mus musculus semaphorin VIa. [AK027471]

2.60

< 0.01

Transcription factor-like 5 (basic helix-loop-helix) (TCFL5) [NM_006602]

2.85

< 0.01

Phosphoinositide-3-kinase, class 3 (PIK3C3) [NM_002647]

2.17

< 0.01

Connective tissue growth factor (CTGF) [NM_001901]

1.93

0.023

EGF-like-domain, multiple 7 (EGFL7) [NM_016215]

1.81

0.039


Genes underexpressed in TEL/AML1 positive ALL


CD9 antigen (p24) (CD9) [NM_001769]

3.72

< 0.01

Lymphocyte-specific protein 1 (LSP1) [NM_002339]

2.82

0.017


The expression of all the selected genes differs by than 1.7-fold between TEL/AML1-positive ALL and TEL/AML1-negative ALL groups.

Gandemer et al. BMC Genomics 2007 8:385   doi:10.1186/1471-2164-8-385

Open Data