Table 2 |
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|
List of the TGFβ1 interactome hubs. |
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|
GB accession ID |
EntrezGene ID |
Gene Symbol |
Gene description |
Log ratio |
|
|
||||
|
7046 |
TGFBR1 |
transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53 kDa) |
1,04 |
|
|
2316 |
FLNA |
filamin A, alpha (actin binding protein 280) |
0,77 |
|
|
2335 |
FN1 |
fibronectin 1 |
0,73 |
|
|
58 |
ACTA1 |
actin, alpha 1, skeletal muscle |
0,62 |
|
|
25 |
ABL1 |
v-abl Abelson murine leukemia viral oncogene homolog 1 |
0,61 |
|
|
7532 |
YWHAG |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide |
0,61 |
|
|
1026 |
CDKN1A |
cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
0,60 |
|
|
5829 |
PXN |
paxillin |
0,58 |
|
|
595 |
CCND1 |
cyclin D1 |
0,55 |
|
|
1739 |
DLG1 |
discs, large homolog 1 (Drosophila) |
0,54 |
|
|
3312 |
HSPA8 |
heat shock 70 kDa protein 8 |
0,49 |
|
|
836 |
CASP3 |
caspase 3, apoptosis-related cysteine peptidase |
0,45 |
|
|
6464 |
SHC1 |
SHC (Src homology 2 domain containing) transforming protein 1 |
0,45 |
|
|
7185 |
TRAF1 |
TNF receptor-associated factor 1 |
0,44 |
|
|
5781 |
PTPN11 |
protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) |
0,42 |
|
|
3667 |
IRS1 |
insulin receptor substrate 1 |
0,25 |
|
|
7057 |
THBS1 |
thrombospondin 1 |
0,20 |
|
|
2130 |
EWSR1 |
Ewing sarcoma breakpoint region 1 |
-0,46 |
|
|
6850 |
SYK |
spleen tyrosine kinase |
-0,48 |
|
|
5359 |
PLSCR1 |
phospholipid scramblase 1 |
-0,48 |
|
|
857 |
CAV1 |
caveolin 1, caveolae protein, 22 kDa |
-0,50 |
|
|
1499 |
CTNNB1 |
catenin (cadherin-associated protein), beta 1, 88 kDa |
-0,56 |
|
|
4088 |
SMAD3 |
SMAD, mothers against DPP homolog 3 (Drosophila) |
-0,62 |
|
|
60 |
ACTB |
actin, beta |
-0,63 |
|
|
6772 |
STAT1 |
signal transducer and activator of transcription 1, 91 kDa |
-0,94 |
|
|
11030 |
RBPMS |
RNA binding protein with multiple splicing |
-0,97 |
|
|
596 |
BCL2 |
B-cell CLL/lymphoma 2 |
-1,41 |
|
|
|
||||
|
Columns show: the GenBank accession number, the EntrezGene ID, the Gene symbol, the gene's description and the geometric mean of the log2 ratio given in Additional file 1, column N, indicating the level of gene expression. |
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|
Campanaro et al. BMC Genomics 2007 8:383 doi:10.1186/1471-2164-8-383 |
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