Table 2

Top 15 genes identified by ratio from the array dataset

UG cluster ID
SwissProt Accession
Gene name
MFS NI
UC NI
Ratio MFS/UC
q-value

Hs.146688
PTGES:O14684
Prostaglandin E synthase
185
108
1.71
1.36E-03
Hs.90303
TSC2:P49815
Tuberous sclerosis 2
60
37
1.64
1.26E-04
Hs.1872
PCK1:P35558
Phosphoenolpyruvate carboxykinase 1
249
157
1.59
4.11E-03
Hs.310545
SYT1:P21579
Synaptotagmin I
109
69
1.57
2.60E-03
Hs.144700
EFNB1:P98172
Ephrin-B1
296
191
1.56
4.84E-03
Hs.334534
GNS:P15586
Glucosamine (N-acetyl)-6-sulfatase
173
112
1.54
5.23E-05
Hs.386283
ADAM12:O43184
Meltrin L
44
73
1.65-1
5.08E-09
Hs.516646
CREB1:P16220
CAMP responsive element BP 1
193
339
1.76-1
1.96E-05
Hs.489142
COL1A2:P08123
Collagen, type I, alpha 2
3663
6582
1.80-1
4.48E-06
Hs.146447
FBN1:P35555
Fibrillin 1
124
233
1.89-1
2.52E-10
Hs.250581
SMARCD2:Q92925
SWI/SNF D2
1532
2963
1.93-1
5.99E-06
Hs.432862
MARCH-VI:O60337
RING-CH protein VI
2091
4245
2.03-1
4.97E-09
Hs.55967
SHOX2:O60902
Short stature homeobox 2
58
137
2.38-1
1.13E-12
Hs.443625
COL3A1:P02461
Collagen, type III, alpha 1
638
1538
2.41-1
2.06E-04
Hs.252418
ELN:P15502
Elastin
35
117
3.34-1
2.19E-08

Unigene ID identifies significant, differentially expressed genes based on expression ratio criteria. The top 6 down regulated and 9 up regulated genes are included. The normalized intensity (NI) from the phosphorimager scan is listed to give a sense of the expression range. The q values are computed based on t test p values. In this and subsequent tables, we show all ratios less than 1 as reciprocals. The entire 4132 gene list has been deposited into GEO (the Gene Expression Omnibus), accession number GSE8759.

Yao et al. BMC Genomics 2007 8:319   doi:10.1186/1471-2164-8-319