Table 6 |
||||||
|
Equine RNASEL single nucleotide polymorphisms |
||||||
|
Region |
Accession EF070193 |
Alleles |
Residue |
Amino Acid Type |
Frequency |
Polymorphism |
|
|
||||||
|
- |
143 |
C |
- |
- |
0.12 |
Transversion |
|
G |
0.88 |
|||||
|
5' UTR |
1857 |
A |
- |
- |
0.55 |
Transversion |
|
C |
0.45 |
|||||
|
Exon 2 |
1991 |
C |
27His |
Basic Polar |
0.54 |
Transition |
|
T |
27Tyr |
Uncharged Polar |
0.46 |
|||
|
Exon 2 |
2020 |
C |
36Gly |
Uncharged Polar |
0.92 |
Transition |
|
T |
36Gly |
0.08 |
||||
|
Exon 2 |
2021 |
G |
37Asp |
Acidic Polar |
0.69 |
Transversion |
|
T |
37Tyr |
Uncharged Polar |
0.31 |
|||
|
Exon 2 |
2118 |
A |
69Asn |
Uncharged Polar |
0.29 |
Transversion |
|
C |
69Thr |
Uncharged Polar |
0.71 |
|||
|
Exon 2 |
2121 |
A |
70Tyr |
Uncharged Polar |
0.92 |
Transition |
|
G |
70Cys |
Uncharged Polar |
0.08 |
|||
|
Exon 2 |
2316 |
A |
135Lys |
Basic Polar |
0.75 |
Transversion |
|
C |
135Thr |
Uncharged Polar |
0.25 |
|||
|
Exon 2 |
2332 |
A |
140Ala |
Nonpolar |
0.35 |
Transition |
|
G |
140Ala |
0.65 |
||||
|
Exon 2 |
2374 |
G |
154Arg |
Basic Polar |
0.83 |
Transversion |
|
T |
154Ser |
Uncharged Polar |
0.17 |
|||
|
Exon 2 |
2635 |
A |
241Thr |
Uncharged Polar |
0.21 |
Transition |
|
G |
241Thr |
0.79 |
||||
|
Exon 2 |
2680 |
C |
256Ser |
Uncharged Polar |
0.43 |
Transversion |
|
G |
256Ser |
0.57 |
||||
|
Exon 2 |
2771 |
A |
287Lys |
Basic Polar |
0.57 |
Transition |
|
G |
287Glu |
Acidic Polar |
0.43 |
|||
|
Exon 2 |
3144 |
A |
411Asn |
Uncharged Polar |
0.19 |
Transition |
|
G |
411Ser |
Uncharged Polar |
0.81 |
|||
|
Exon 2 |
3152 |
C |
414Arg |
Basic Polar |
0.81 |
Transition |
|
T |
414Cys |
Uncharged Polar |
0.19 |
|||
|
Exon 2 |
3281 |
A |
457Lys |
Basic Polar |
0.19 |
Transition |
|
G |
457Glu |
Acidic Polar |
0.81 |
|||
|
Exon 2 |
3301 |
A |
463Lys |
Basic Polar |
0.19 |
Transversion |
|
C |
463Asn |
Uncharged Polar |
0.81 |
|||
|
Exon 2 |
3311 |
C |
467Pro |
Nonpolar |
0.19 |
Transition |
|
T |
467Ser |
Uncharged Polar |
0.81 |
|||
|
Exon 2 |
3372 |
A |
487Gln |
Uncharged Polar |
0.58 |
Transition |
|
G |
487Arg |
Basic Polar |
0.42 |
|||
|
Intron 2 |
3404 |
A |
- |
- |
0.19 |
Transition |
|
G |
0.81 |
|||||
|
Exon 3 |
5108 |
A |
513Lys |
Basic Polar |
0.11 |
Transition |
|
G |
513Glu |
Acidic Polar |
0.89 |
|||
|
Exon 3 |
5111 |
C |
514Pro |
Nonpolar |
0.82 |
Transition |
|
T |
514Ser |
Uncharged Polar |
0.18 |
|||
|
Exon 5 |
7314 |
A |
598Asn |
Uncharged Polar |
0.87 |
Transition |
|
G |
598Asp |
Acidic Polar |
0.13 |
|||
|
3' UTR |
9994 |
C |
- |
- |
0.15 |
Transversion |
|
G |
0.85 |
|||||
|
3' UTR |
9999 |
A |
- |
- |
0.88 |
Transversion |
|
T |
0.12 |
|||||
|
3' UTR |
10247 |
C |
- |
- |
0.31 |
Transition |
|
T |
0.69 |
|||||
|
3' UTR |
10914 |
C |
- |
- |
0.38 |
Transition |
|
T |
0.62 |
|||||
|
3' UTR |
11105 |
C |
- |
- |
0.88 |
Transition |
|
T |
0.12 |
|||||
|
3' UTR |
11146 |
C |
- |
- |
0.35 |
Transition |
|
T |
0.65 |
|||||
|
3' UTR |
11184 |
C |
- |
- |
0.35 |
Transition |
|
T |
0.65 |
|||||
|
3' UTR |
11228 |
C |
- |
- |
0.83 |
Transition |
|
T |
0.17 |
|||||
|
|
||||||
|
SNPs identified from sequencing RNASEL exons from 13 equine individuals, CHORI BAC 159N12 and the reference transcript sequence. Positions are identified from the genomic consensus sequence submitted to GenBank [GenBank: EF070193]. |
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|
Rios et al. BMC Genomics 2007 8:313 doi:10.1186/1471-2164-8-313 |
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