Table 1

List of Phlebotomus papatasi midgut-specific sequences, clusters, and sequences per cluster of cDNA libraries made from flies sugar-fed, blood-fed, and blood fed with Leishmania major parasites

Number of Clusters
 Number of Sequences
 Sequences/cluster
Biological function
 Sugar
 Blood-fed
 L. major
 Sugar
 Blood-fed
 L. major
 Sugar
 Blood-fed
 L. major
protein synthesis machinery
 88
 39
 51
 281
 73
 159
 3.19
 1.87
 3.12
protein modification machinery
 19
 20
 8
 39
 22
 9
 2.05
 1.10
 1.13
protein export machinery
 14
 13
 10
 14
 13
 10
 1.00
 1.00
 1.00
transcription machinery
 4
 2
 1
 4
 2
 1
 1.00
 1.00
 1.00
transcription factors
 13
 6
 3
 22
 9
 4
 1.69
 1.50
 1.33
proteasome machinery
 13
 7
 7
 21
 7
 9
 1.62
 1.00
 1.29
transporters
 24
 16
 11
 37
 19
 33
 1.54
 1.19
 3.00
extracellular matrix
 6
 12
 5
 164
 122
 59
 27.33
 10.17
 11.80
cytoskeletal
 16
 15
 14
 61
 291
 210
 3.81
 19.40
 15.00
signal transduction
 28
 20
 13
 38
 20
 15
 1.36
 1.00
 1.15
protease inhibitor
 3
 1
 3
 8
 5
 9
 2.67
 5.00
 3.00
immunity
 3
 4
 3
 8
 5
 4
 2.67
 1.25
 1.33
adhesion
 1
 2
 1
 1
 2
 1
 1.00
 1.00
 1.00
nuclear metabolism and regulation
 17
 7
 6
 18
 9
 6
 1.06
 1.29
 1.00
metabolism, energy
 95
 38
 42
 194
 54
 62
 2.04
 1.42
 1.48
metabolism, lipid
 9
 11
 9
 11
 18
 10
 1.22
 1.64
 1.11
metabolism, carbohydrate
 16
 9
 10
 27
 12
 14
 1.69
 1.33
 1.40
metabolism, amino acid
 28
 40
 30
 131
 182
 197
 4.68
 4.55
 6.57
metabolism, nucleic acid and nucleotides
 7
 9
 4
 14
 9
 4
 2.00
 1.00
 1.00
metabolism, heme
 3
 3
 2
 8
 28
 8
 2.67
 9.33
 4.00
conserved of unknown function
 262
 167
 322
 405
 282
 470
 1.55
 1.69
 1.46
Total
 669
 441
 555
 1506
 1184
 1294
 Avg 3.23
 Avg 3.27
 Avg 3.01

Ramalho-Ortigão et al. BMC Genomics 2007 8:300   doi:10.1186/1471-2164-8-300