Table 3

Reversible gene expression upon smoking cessation related to mucus secretion (genes in bold have not been previously associated with smoking)

Tag

Gene Symbol

Gene Name

CS Mean*

FS Mean*

NS Mean*

P-Value (CVsF)


GAATGAACTG

EDIL3

EGF-like repeats and discoidin I-like domains 3

72

5

8

0.00011

CTCCACCCGA

TFF3

Trefoil factor 3 (intestinal)

4974

1978

1722

0.00019

GTGGAGAAGA

CLDN10

Claudin 10

89

23

26

0.00019

GGAATTGCCC

BPIL1

Bactericidal/permeability-increasing protein-like 1

43

4

4

0.00029

TTGGTTTTTG

CXCL6

Chemokine (C-X-C motif) ligand 6

147

414

371

0.0003

CCTATCAGTA

MSMB

Microseminoprotein, beta-

15881

4405

2948

0.00048

CTTCCTGTGA

SBEM

Small breast epithelial mucin

154

27

32

0.00071

TGGAAATGTG

CBARA1

Calcium binding atopy-related autoantigen 1

49

18

15

0.00141

CAAGCATAAA

CABYR

Calcium binding tyrosine-(Y)-phosphorylation regulated

63

4

4

0.00241

AGGGAGGCAG

SCGB1A1

Secretoglobin, family 1A, member 1

135

473

436

0.0041

TATCACATTC

CXCL6

Chemokine (C-X-C motif) ligand 6

10

42

29

0.00573

TTGCACCCTT

MSMB

Microseminoprotein, beta-

71

16

9

0.00735

AGCTTAATGA**

SCGB1A1

Secretoglobin, family 1A, member 1

557

1478

3269

0.00956

GAAAAAATAG

SCGB1A1

Secretoglobin, family 1A, member 1 (uteroglobin)

88

288

281

0.0124

GTGGCCACGG

S100A9

S100 calcium binding protein A9 (calgranulin B)

26

101

63

0.0124

AAAATGTATT

CAV2

Caveolin 2

20

6

4

0.0144

GACAAGGATG

CX3CL1

Chemokine (C-X3-C motif) ligand 1

29

63

93

0.01586


*Mean in tags per million (TPM)

** Changed mapping with TAGMapper [56]

Chari et al. BMC Genomics 2007 8:297   doi:10.1186/1471-2164-8-297

Open Data