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Open Access Highly Accessed Research article

Effect of active smoking on the human bronchial epithelium transcriptome

Raj Chari1*, Kim M Lonergan1, Raymond T Ng2, Calum MacAulay3, Wan L Lam1 and Stephen Lam3

Author Affiliations

1 Department of Cancer Genetics and Developmental Biology, British Columbia Cancer Research Centre, Vancouver, BC, Canada

2 Department of Computer Science, University of British Columbia, Vancouver, BC, Canada

3 Department of Cancer Imaging, British Columbia Cancer Research Centre, Vancouver, BC, Canada

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BMC Genomics 2007, 8:297  doi:10.1186/1471-2164-8-297

Published: 29 August 2007

Additional files

Additional file 1:

Supplementary Table 1 – Tags expressed in all current smoker libraries. Tags which have a raw count of greater than 2 in all 8 current smoker SAGE libraries.

Format: XLS Size: 65KB Download file

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Additional file 2:

Supplementary Table 2 – Tags expressed in all former smoker libraries. Tags which have a raw count of greater than 2 in all 12 former smoker SAGE libraries.

Format: XLS Size: 33KB Download file

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Additional file 3:

Supplementary Table 3 – Tags expressed in all never smoker libraries. Tags which have a raw count greater than 2 in all 4 never smoker SAGE libraries.

Format: XLS Size: 412KB Download file

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Additional file 4:

Supplementary Table 4 – Tags expressed in all 24 SAGE libraries. Tags which have a raw count greater than 2 in all 24 SAGE libraries.

Format: XLS Size: 474KB Download file

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Additional file 5:

Supplementary Table 5 – 609 tags differentially expressed between current and never smokers. 609 differentially expressed tags between current and never smokers.

Format: XLS Size: 196KB Download file

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Additional file 6:

Supplementary Table 6 – 161 tags with reversible expression upon smoking cessation. 161 tags which exhibit statistically reversible gene expression upon smoking cessation.

Format: XLS Size: 41KB Download file

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Additional file 7:

Supplementary Table 7 – 152 tags with irreversible expression upon smoking cessation. 152 tags which exhibit statistically irreversible gene expression upon smoking cessation.

Format: XLS Size: 45KB Download file

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Additional file 8:

Supplementary Table 8 – 157 tags differentially expressed between mild and moderate/severe COPD.

Format: XLS Size: 46KB Download file

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Additional file 9:

Supplementary Table 9 – Cycle threshold data from quantitative RT-PCR. Raw cycle threshold data for quantitative RT-PCR of 5 genes.

Format: XLS Size: 27KB Download file

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Additional file 10:

Supplementary Table 10 – Fold-changes and p-values from quantitative RT-PCR analysis. Data from the analysis of the quantitative RT-PCR results.

Format: XLS Size: 14KB Download file

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Additional file 11:

Supplementary Table 11 – Quantitative RT-PCR primers. Primers ordered from Applied Biosystems for 5 genes.

Format: XLS Size: 20KB Download file

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