Table 1

Characteristics of subjects

Sample ID

Sample Type

Order Code

Chief Disease

Cause of Death

Age [years/days]

Gender

Race

PMI [h]


Control 1

tissue

BTB3428 A

drowning

drowning

56/275

Female

Caucasian

17

Control 2

tissue

BTB3576A

hypertension

ruptured abdominal aortic aneurism

59/260

Male

Caucasian

15

Control 3

tissue

BTB3577A

n/a

n/a

59/118

Male

Caucasian

21

Control 4

tissue

BTB3688A

ascending colon adenocarcinoma

ascending colon adenocarcinoma

60/-

Male

Hispanic White

17

Control 5

tissue

HCtANA

n/a

n/a

72/-

Male

Caucasian

11

Control 6

tissue

HCtAVA

n/a

n/a

84/-

Female

Caucasian

2.75

Control 7

tissue

HCtEUA

coronary artery disease

n/a

79/-

Female

Caucasian

7.5

Control 8

tissue

HCtFMA

n/a

n/a

70/-

Female

Caucasian

8.5

Control 9

RNA

6782B

thrombosis and coronary atherosclerosis

heart attack

68/-

Male

Caucasian

n/a

Diseased 1

tissue

BTB3226 A

ALS

respiratory failure with probable early pneumonia

71/18

Male

Caucasian

19

Diseased 2

tissue

BTB3235 A

ALS

respiratory failure

73/106

Male

Caucasian

5.5

Diseased 3

tissue

BTB3461 A

ALS

ALS

77/53

Male

Caucasian

7.5

Diseased 4

tissue

BTB3580A

ALS

respiratory failure

58/83

Male

Caucasian

22

Diseased 5

tissue

BTB3583A

ALS

respiratory distress

52/54

Female

Hispanic White

20.5

Diseased 6

tissue

BTB3590A

ALS

pneumonia

75/-

Male

Caucasian

24

Diseased 7

tissue

BTB3603A

ALS

N/A

67/325

Female

Caucasian

17

Diseased 8

tissue

BTB3611A

ALS

N/A

69/90

Female

Caucasian

13

Diseased 9

tissue

BTB3689A

ALS

N/A

61/141

Female

Caucasian

22

Diseased 10

tissue

BTB3713A

ALS

ALS

66/252

Male

Caucasian

13

Diseased 11

RNA

6166B

ALS

respiratory failure

70/-

Male

Caucasian

n/a


20 motor-cortex samples of eleven ALS patients and nine controls were analyzed on individual Whole Human Genome Arrays for genome-wide expression profiling. Age, gender, race, and post-mortem interval (mean controls 12.47 ± 6.06 h and mean patients 16.35 ± 6.37 h, P = 0.21) are shown for all tissue samples. A – Miami Brain and Tissue Bank for Developmental Disorders; B – Ambion, Inc.; n/a – not available

Lederer et al. BMC Genomics 2007 8:26   doi:10.1186/1471-2164-8-26

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