Figure 7.

The interplay of cell types and pathways in SALS pathology. Combining pathways and candidate genes differentially expressed in the motor cortex of SALS patients reveals a complex interplay of cellular processes and cell types. Candidate genes corresponding to major pathways discussed in the main text are color-coded, placed in the cell type(s) where they most likely exert their influence, and their individual up- () or down-regulation () is indicated. Genes EIF4A2, GNAS, and NAP1L5 are left out for clarity.

Lederer et al. BMC Genomics 2007 8:26   doi:10.1186/1471-2164-8-26
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