Comparison of microarray and qRT-PCR results for selected candidate genes. The bar graph shows mean results of expression levels in SALS vs. control subject. Fold-changes are shown diseased vs. control, and differed by less than 1.2-fold between qRT-PCR and microarray, except for MT1E and MT2A. Error bars for qRT-PCR data indicate the range for duplicate experiments. The P values for qRT-PCR and microarray (most significant probe) data were 0.342 and 0.020 (MT1E), 0.063 and 0.023 (MT1G), 0.037 and 0.025 (MT1L), 0.119 and 0.026 (MT1M), 0.074 and 0.031 (MT1X), 0.063 and 0.011 (MT2A), and 0.037 and 0.011 (PVALB).
Lederer et al. BMC Genomics 2007 8:26 doi:10.1186/1471-2164-8-26