Table 3

Negatively affected transcription factors in the long-lived mutants. The "num" column indicates the number of target genes of a transcription factor under a specific condition at the 0.01 significance level according to the ChIP-chip data.

Transcription Factor

Condition

Num

sch9Δ/wt

ras2Δ/wt

tor1Δ/wt

p-value

q-value

p-value

q-value

p-value

q-value


ABF1

YPD

549

1.9E-04

0.012

6.1E-07

9.6E-05

1.6E-07

3.2E-05

GCN4

RAPA

324

0.77

0.90

0.031

0.26

1.3E-09

4.2E-07

GCN4

YPD

143

0.16

0.43

0.0031

0.052

9.2E-11

3.6E-08

HAP4

YPD

126

4.2E-06

5.5E-04

0.0013

0.040

1.2E-05

0.0011

INO2

YPD

114

1.2E-05

0.0011

0.0038

0.056

0.0014

0.040

RTG3

RAPA

158

0.0016

0.038

9.9E-05

0.0059

1.3E-05

0.0010


Cheng et al. BMC Genomics 2007 8:219   doi:10.1186/1471-2164-8-219

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