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Open Access Highly Accessed Research article

Characterization of microRNA expression profiles in normal human tissues

Yu Liang*, Dana Ridzon, Linda Wong and Caifu Chen

Author Affiliations

Molecular and Cell Biology-R&D, Applied Biosystems, Foster City, CA 94404, USA

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BMC Genomics 2007, 8:166  doi:10.1186/1471-2164-8-166

Published: 12 June 2007

Additional files

Additional file 1:

Complete data of miRNA expression in 40 normal human tissues. Complete data normalized by the least variable miRNAs and small nuclear RNAs.

Format: XLS Size: 391KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 2:

The clustering patterns of normal human tissues using mRNA expression profiles. The clustering patterns of normal human tissues using mRNA expression profiles taken from Shyamsunder et al. [18].

Format: PDF Size: 62KB Download file

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Open Data

Additional file 3:

Differential abundance of miRNAs in normal human tissues. A color-coded diagram illustrates the differential abundance of miRNAs in normal human tissues. Normal tissues were generally arranged by their positions in human body, as highlighted at the right side of the diagram, whereas miRNAs were sorted based upon their annotated ID.

Format: TIFF Size: 5.3MB Download file

Open Data

Additional file 4:

Estimated copy numbers of miRNAs in normal human tissues. Complete data of estimated copy numbers of miRNAs in normal human tissues transformed from the Additional file 1.

Format: XLS Size: 219KB Download file

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Open Data

Additional file 5:

The "regulogram" of the genomic sequence close to the hsa-miR-1-2 locus where MyoD binding site was identified. The "regulogram" from GenomeTraFac showed the genomic sequence close to the hsa-miR-1-2 locus where MyoD binding site was identified.

Format: PDF Size: 967KB Download file

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Open Data

Additional file 6:

Expression patterns of INSM1, STAT5, and SOX5 in normal human tissues. Expression patterns of INSM1, STAT5, and SOX5 in normal human tissues from the GNF database.

Format: PDF Size: 983KB Download file

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Open Data

Additional file 7:

Binding sites for Nkx2-5, SOX5, and FOXF2 and their tissue distribution. Binding sites for Nkx2-5, SOX5, and FOXF2 from GenomeTraFac, and their tissue distribution from the GNF database.

Format: PDF Size: 1.9MB Download file

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Open Data

Additional file 8:

Phenotypic data for the refined list of predicted target genes of miR-199a/199b/214. Complete phenotypic data extracted from IGTC for the refined list of predicted target genes of miR-199a/199b/214.

Format: XLS Size: 21KB Download file

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Open Data