Email updates

Keep up to date with the latest news and content from BMC Genomics and BioMed Central.

Open Access Highly Accessed Research article

NGF-mediated transcriptional targets of p53 in PC12 neuronal differentiation

Christopher Brynczka12, Paul Labhart3 and B Alex Merrick1*

Author Affiliations

1 National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA

2 Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, North Carolina 27606, USA

3 Genpathway, Inc., San Diego, California 92121, USA

For all author emails, please log on.

BMC Genomics 2007, 8:139  doi:10.1186/1471-2164-8-139

Published: 31 May 2007

Additional files

Additional File 1:

Supplementary Data. A Supplementary data file is included that contains 5 figures and 4 tables. The 5 figures contain additional biological data (Figures 1, 2 and 3) and bioinformatic data (Figure 4) as well as a diagram of the ChIP cloning procedure (Figure 5). The tables contain ChIP statistics (Table 1), ChIP primers (Table 2), a list of p53-occupied regions that were non-NGF responsive (Table 3) and RT-PCR primers (Table 4).

Format: PDF Size: 198KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional File 2:

Cluster Coordinates. A detailed data spreadsheet is included that contains cluster coordinates, chromosome number, and DNA sequences for 212 clusters and roughly 700 associated DNA sequence tags derived from p53 chromatin immunoprecipitation (ChIP) analysis of the rat genome.

Format: XLS Size: 190KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data