Figure 3.

Functional classification of CAGpolyQ genes: shared Gene Ontology term analysis. Known disease genes are marked with a 'D', candidate disease genes are marked with a 'C' and genes with invariant Q-tracts (Table 1) are marked with an 'I'. Clusters of genes are labeled with the GO terms that best described each cluster. GO terms shared by gene pairs are listed in Additional file 7 and Additional file 8. Genes not represented in a graph either had no annotation under that GO namespace or did not share a GO term with a score above the 99^th percentile. (A) Biological process. Genes not represented: ARID1B, ATXN1, ATXN2, BRD4, C9ORF43, DCP1B, HD, DENND4B, FRMPD3, MAML2, PAXIP1L, PHC1, PHLDA1, SOCS7, THAP11, TNRC15, TNRC6A, TNRC6B and TNS. (B) Molecular function. Genes not represented: ATN1, ATXN1, ATXN3, BRD4, C14ORF4, C9ORF43, CHERP, DCP1B, KCNN3, DENND4B, FRMPD3, MAML2, NUMBL, PAXIP1L, PCQAP, PHLDA1, SOCS7, ST6GALNAC5, TNRC15, TNRC6A, TNRC6B and TNS.